Comparison of quality of survival between children randomly allocated to different treatments for medulloblastoma (Dr. Colin Kennedy)
3 year project with grant funding of £74,752.00
2001 - 2004
Treatment given to children diagnosed with a brain tumour often has unwanted effects that reduce the child to function well or to enjoy life. It is important to know what these abilities are in large numbers of treated children and in order to come to reliable conclusions about the likely effect of any particular treatment. The most reliable way to know if two treatments differ in their effect on the child’s long term abilities is to give the child one or other of two possible treatments in a “randomized controlled trial” (RCT) and then compare the outcomes in the two groups. It is extremely important to find out how the treatments compare in their effects on the children’s long term abilities.
The aim of this project is to ask children (some of whom are now adults) enrolled in studies, to answer a relatively small number of questions in questionnaires and at the same time to allow team treating these children all across Europe to become used to using this method so that they will collect this information as they go along in SIOP4, the next trial of treatment for medulloblastoma, which will start in 2002.
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