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Current SDBTT Funded Research

Over £1.5 million in new research for 2006

Our last funding round included 34 high quality applications. These were externally peer reviewed by experts in the field of neurology in the UK, Europe , USA and Canada. Over 100 specialists helped SDBTT to review all the applications in a concerted effort to make sure our funding is being used to the best advantage.

Please click on the institution name to read about the project in layman's term.

Research:    A genome wide methylation analysis of oligodendroglial tumours
Team: Dr Koichi Ichimura, UNIVERSITY OF CAMBRIDGE
Funding: SDBTT & Brain Tumour Foundation* also in memory of Catherine Philpott £175,000
     
Research: Reassessing the origins of cranial germ cell tumours
Team: Dr Paul Scotting, UNIVERSITY OF NOTTINGHAM
Funding: SDBTT £97,892
     
Research: Detailed analysis of two genetically altered regions of the genome in astrocytic gliomas by means of chromosomal tile path array-CGH
Team: Professor Peter Collins, UNIVERSITY OF CAMBRIDGE
Funding: SDBTT Gordon Lambert Fund & SDBTT Gordon King Fund £147,000
     
Research: Radiological and molecular markers of subsequent behaviour in adult low-grade glioma
Team: Dr Tracy Warr, INSTITUTE OF NEUROLOGY, LONDON  
Funding: SDBTT Astro Fund £99,092
     
Research: Advanced magnetic resonance imaging and metabolic studies of low grade gliomas of childhood  
Team: Professor Richard Grundy, UNIVERSITY OF NOTTINGHAM  
Funding: SDBTT Astro Fund £117,789
     
Research: UK case control study of possible causes of brain tumours of children, teenagers and young adults: A pilot study  
Team: Professor Patricia McKinney, UNIVERSITY OF LEEDS  
Funding: SDBTT & SDBTT Geert Cloet Fund £91,405
     
Research: Wnt signalling in neural stem cell differentiation and tumourigenesis of the CNS. Initial study  
Team: Professor S Brandner, INSTITUTE OF NEUROLOGY, LONDON  
Funding: SDBTT £114,445
     
Research: Imaging of molecular dynamics and cell fate to identify new targets for medulloblastoma therapy  
Team: Dr Violaine Sée, UNIVERSITY OF LIVERPOOL  
Funding: SDBTT £145,838
     
Research: Development and evaluation of a neuropsychological follow-up service for survivors of childhood brain tumours  
Team:

Professor Christine Eiser, UNIVERSITIES OF SHEFFIELD &BRISTOL

 
Funding: SDBTT & Clowns in the Sky £29,755
     
Research: Determination of Clomipramine levels in the brains of glioma patients using intracranial microdialysis  
Team: Professor Garth Cruickshank, QUEEN ELIZABETH HOSPITAL BIRMINGHAM  
Funding: SDBTT £26,962
     
Research: The contribution of drug resistant cancer stem cells to paediatric brain tumours  
Team: Dr Beth Coyle, UNIVERSITY OF NOTTINGHAM  
Funding: SDBTT & Brain Tumour Foundation* £147,001
     
Research: Comprehensive mapping of gene expression and genomic gains and losses in paediatric high grade gliomas and the contribution of drug resistant cancer cells  
Team: Professor Richard Grundy, UNIVERSITY OF NOTTINGHAM  
Funding: SDBTT £83,363
     
Research: Introduction of guidance to shorten symptom interval and enhance access to diagnostic pathways for CNS tumours in children and young adults and evaluation by prospective observational cohort study. (This is an extension for one year on the original project 'Tracking delays in diagnosis').  
Team: Professor David Walker, UNIVERSITY OF NOTTINGHAM  
Funding: SDBTT £44,479
     
     

Commencing in 2007

Research:    Targeting the Nuclear Factor-kappaB (NF-kB) pathway to improve chemotherapy of glioblastoma multiforme
Team: Professor John Darling, UNIVERSITY OF WOLVERHAMPTON
Funding: SDBTT
£144,921
     
Research: The Molecular basis of childhood medulloblastoma: from genomics to improved therapies
Team: Dr. Steven Clifford, UNIVERSITY OF NEWCASTLE-UPON-TYNE
Funding: SDBTT
£185,112
     
Research: Molecular genetic and epigenetic analysis of paediatric low grade gliomas
Team: Professor Denise Sheer INSTITUTE OF CELL AND MOLECULAR SCIENCE, BARTS AND THE LONDON
Funding SDBTT
£56,981
     
Research Rates of psychiatric illness in long-term survivors of early childhood brain tumorus
Team: Dr Howard Ring, UNIVERSITY OF CAMBRIDGE
Funding SDBTT
£95,108

 

 

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